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Laszlo GS, Estey EH, Walter RB

38-40 In addition, IC/BPS patients have significantly more pain, sleep dysfunction, catastrophizing, depression, anxiety, stress, social functioning difficulties and sexual dysfunction than do non-IC/BPS age-matched women

Notably, an impressive 91.9% of patients in the combination therapy group achieved at least 5% weight loss, with 53.6% achieving 20% and 34.7% achieving 25%

8 A case-control study that compared 25,956 patients who had vitamin B 12 deficiency with 184,199 control patients found a significantly increased risk of vitamin B 12 deficiency in patients who had taken proton pump inhibitors (odds ratio = 1.65) or histamine H 2 blockers (odds ratio = 1.25) for at least two years