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Modifiable Risk Factors Environmental exposures constitute significant modifiable risk factors for PD

This would seem to be a potentially fruitful area for further research since the major environmental risk factors for PDexposure to pesticides, trichloroethylene, and air pollutionare likely to have their effects on dopaminergic neurodegeneration via toxic effects of oxidative stress and inflammation 61

These data show that prolonged intestinal inflammation is associated with a protumorigenic, inflammatory, and rich prostatic phenotype, which may explain how IBD males acquire PCa

Looking forward, the integration of complementary technologies bulk, single-cell, spatial, and multi-omics together with computational modeling will be critical for connecting molecular-level discoveries in MuSC biology to systemic physiology and, eventually, to translational interventions for muscle aging