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Liu Q, Li J, Cheng R, et al
The combination of anti-angiogenic drugs and chemotherapy drug docetaxel can effectively inhibit the synthesis of mitochondrial DNA in hypoxic tumor stem cells, thereby improving the efficacy of anti-angiogenic drugs (187)
AOD 9604 clinical trials showed a tolerability profile statistically indistinguishable from placebo

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment