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acnes vitamin B12 biosynthesis pathway in vivo , we conducted a longitudinal study, in which the gene expression of the skin microbiota in healthy subjects with vitamin B12 supplementation was analyzed

High levels of B12, or hypercobalaminemia, can be a sign of tissue breakdown, which releases B12 back into the bloodstream

5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that plays a central role in NAD+ metabolism and cellular energy balance

These experimental frameworks are used to investigate how multiple pathways contribute to tissue remodeling and cellular differentiation processes under controlled conditions