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Additionally, curcumin appears to hinder the proteolytic processing of SREBP-2, leading to decreased production of the mature SREBP-2 (mSREBP-2) and altering the cellular distribution of SREBP-2 (93)

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The cohorts spanned lung, colon, kidney, bladder and skin cancer, covering diverse treatment strategies, such as ICI with or without FMT, chemotherapy (CT), radiotherapy (RX) and/or tyrosine kinase inhibitors (TKIs) (Supplementary Table 1ak)