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5 1 As a review: Glutamate binds to and activates several glutaminergic ion channels on postsynaptic neurons, but it is the NMDAR that is implicated in the development of chronic pain

The trigger is the combination of rapid weight loss and caloric restriction: when appetite suppression is working well, patients are eating significantly less, and if protein and micronutrient intake fall below what the body needs, hair follicles are among the first structures deprioritized
Int J Pharm Yehuda S, Carasso RL (1988) DSIP: brain mechanisms and function
