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It was found that ALPPS surgery caused an increase in IHH secreted by activated HSCs, and activated the HH signaling pathway in hepatocytes to promote the accumulation of GLI1 in the nucleus, thereby promoting LR (Langiewicz et al., 2017

A systematic review has summarized the diverse functions of miRNAs in the auditory system, including their roles in hair cell development, survival, and responses to acoustic trauma, positioning miRNAs as key regulators of auditory homeostasis and potential contributors to tinnitus (Ebbers et al., 2022)
SAC regulates glutathione metabolism via the Keap1/Nrf2/GPX4 signaling pathway to inhibit ferroptosis and alleviate ulcerative colitis

The Two Main MTHFR SNPs Genetic variations in the MTHFR gene results in reduced activity of the enzyme produced and have been associated with a series of diseases and conditions, including cardiovascular disorders, neurological defects, some forms of cancer, psychiatric disorders, diabetes, and pregnancy complications [3, 4]
