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Description
We conducted separate analyses for male and female sex to derive sex-specific estimates of the breakpoints

Several microbially derived metabolites have been associated with elevated CVD risk, including phenylacetylglutamine (20), imidazole propionate (21), and trimethylamine (TMA) (10, 22)

Dermatology 195 , 1019 (1997)

This implies that deviations from mitochondrial homeostasis manifest differently and have varying consequences across cell types
