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Significant improvements in 24-h urine output levels and urinary protein, albumin to creatinine ratio, and Scr levels and a decrease in glomerular mesangial zone collagen fibers and lipid accumulation were observed in renal tissue samples (222)

A phase II randomized controlled trial demonstrated that deferiprone, an iron chelator, significantly reduced iron accumulation in the substantia nigra accompanied by measurable improvements in motor function assessed by UPDRS [259]

The intestinal absorption of Mg tends to decline with age, which may contribute to Mg deficits in aging individuals [33]

Clinical characteristics and predictors of progression of chronic kidney disease in autosomal dominant polycystic kidney disease: a single center experience