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These models also enable the analysis of tumour-subtype specificity, interplay with chemotherapeutic or targeted compounds and potential organ-specific toxicities such as hepatic-, nephro- and cardiovascular-toxicity
It was explained that the percentage of cancer cells in total cells of cHL is small, typically less than 1%, whereas the percentage of cancer cells in DLBCL and solid malignancies is generally between 40 and 80% [42]
Nimmagadda A, Stanley I, Karliner J, Orris P
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