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A (served as the control), B (received 3 mg/kg CdCL2), C (received 100 mg/kg PREOG), D (received 200 mg/kg PREOG), E (received 100 mg/kg PREOG+3 mg/kg CdCL2) and F (received 200 mg/kg PREOG+3 mg/kg CdCL2) treatment continued to postnatal day 29 before weaning

In the development of inflammation, prostaglandins, especially prostaglandin E2 (PGE2), are major players alongside with chemo- and cytokines, like tumor-necrosis-factor alpha (TNF) and interleukin-1 beta (IL-1)