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siRNA potency enhancement via chemical modifications of nucleotide bases at the 5-end of the siRNA guide strand

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However, in contrast to the tumour-suppressive effects described above, there is evidence that CDO1 can have a tumorigenic effect associated with aggressive glioblastoma, since its overexpression was detected in these tumours

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Martins et al

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By encapsulating the active molecule in a protective lipid vesicle, we can shield it from the harsh environment of the digestive tract

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