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Addingly, another study not only showed increased iron concentration in SN pars compacta of early-stage PD patients compared to controls, but in those with late-stage PD apart from affecting SN pars compacta, other areas such as red nucleus and globus pallidus became involved suggesting a regionally progressive accumulation that is consistent with the stage of the disease (Guan et al., 2017)

Otolaryngol Clin North Am 51(3):xix-xx, 2018

Upon further analysis of the samples, it was found that the majority of the samples (69%) originated from the illegal supply chain, while 13% came from the legal supply chain (pharmacies and retail shops), as can be seen in Figure 2b
