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419,420 Mitochondrial iron accumulation, energy imbalance, increased ROS, and lipid peroxidation are all related to the pathogenesis of this disease, suggesting that ferroptosis may be closely related to Friedreichs Ataxia

For example, prohibitin 1 (PHB1) is a ubiquitous protein expressed in multiple subcellular regions but primarily in the inner mitochondrial membrane
doi: 10.1155/2022/4919153

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