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Johnson PM, Kenny PJ (2010) Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

Alpha-MSH plays a key role in the regulation of melanogenesis the process by which the body produces melanin pigment as well as various other physiological processes
Participants on MC4-NN20453 also reported sexual arousal, albeit with low incidence (27%) (57)

MT-1 mainly targets MC1R receptors, leading to slow, steady, and long-lasting changes in skin tone
