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Nat Commun 8: 1174 Hopkins L, Parmar S, Baszczyk A, Hesse H, Hoefgen R, Hawkesford MJ (2005) O-acetylserine and the regulation of expression of genes encoding components for sulfate uptake and assimilation in potato

DNA methylation is modified by environmental factors such as diet that may modify cancer risk and tumor behavior

In vitro studies reinforce these findings, demonstrating pinocembrins protective effects against IH-induced cytotoxicity in microglial cells [175]

Furthermore, siRNA or CRISPR vectors packaged into cell-type-specific vehicles could achieve genetic ferroptosis checkpoint modulation without systemic toxicity