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Promising results, but questions remain Alice Chen, M.D., of NCIs Division of Cancer Treatment and Diagnosis, who led the phase 2 trial of nirogacestat but was not involved in the phase 3 study, said that the findings are very significant, but some questions remain
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The compound incorporates four strategic amino acid substitutions compared to the native GHRH sequence, improving its resistance to enzymatic breakdown while preserving potent receptor binding
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