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Iron homeostasis is regulated and maintained by iron metabolism

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While a number of studies have confirmed a beneficial effect for antioxidants in reversing OS-induced sperm dysfunction specifically in patients with idiopathic male infertility, there are few controlled or randomized clinical trials, thus limiting strong evidence in support of their use

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doi: 10.1080/09168451.2018.1459467 93 MartensN.SchepersM.ZhanN.LeijtenF.VoortmanG.TianeA.et al

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More recent data demonstrate that the production of ROS in mitochondria is by an order of magnitude smaller than originally expected and is approximately 0.15% [15]

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