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Dicembrini I, Nreu B, Montereggi C, Mannucci E, Monami M (2020) Risk of cancer in patients treated with dipeptidyl peptidase-4 inhibitors: an extensive meta-analysis of randomized controlled trials

Studied for its potential to interact with NNMT and influence cellular metabolism in laboratory settings

Patients may be stuck in a chronic state of cyclical inflammation leading to tissue degeneration, refractory symptoms, and disability

The nucleotide-binding domain-like receptor protein 3 (NLRP3) is a necessary inflammation interacting with procaspase-1 and apoptosis-associated speck-like protein (ASC) within the NLRP3 inflammation complex