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Overall, the review highlights metabolism as a key determinant of GBM pathophysiology and a promising target for therapeutic innovation, emphasizing the importance of continued translational research to identify and exploit context-specific metabolic vulnerabilities in this highly lethal disease
Glutathione- 13 C 2 , 15 N used as an IS for glutathione was obtained from Sigma-Aldrich
10.1212/01.WNL.0000154641.08211.B7 33 MuratoreC

The neurotransmitter receptor-anchoring protein gephyrin reconstitutes molybdenum cofactor biosynthesis in bacteria, plants, and mammalian cells
