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Description
One common complication of diabetes is atherosclerosis, a form of arteriosclerosis that causes hardening and inflammation of the arteries caused by high glucose levels
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By its upstream action of inhibiting lipid peroxidation, GPX4 can indirectly but effectively reduce the expression levels of these destructive enzymes, thereby delaying or preventing ECM breakdown (Xiao et al., 2024) (Figure 1)
Trans-activation of PPAR and induction of PPAR target genes by perfluorooctane-based chemicals
