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( 20:1103 ) Li S, Yang C, Wang W et al (2024) First-in-human study to assess the safety, tolerability, and pharmacokinetics of intravenous SHPL-49 following single- and multiple-ascending-dose administration in healthy adults
It is intended strictly for scientific research and is not formulated for human or veterinary use, therapeutic applications, or dietary supplementation
The scavenger receptor class B member 1 (SCARB1) is highly expressed in LN229 cells compared to U87 cells
Dopamine agonists, including rotigotine, ropinirole, and pramipexole directly stimulate dopamine receptors and can delay the need for levodopa in early-stage PD 53,54
