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Description
For most patients, yes
The additionally calculated stimulation index (SI) of ROS-producing PMN ( Supplementary Table 3 ) showed a biphasic time course with a minimum at 1 h pi and a maximum at 12 h pi

doi:10.1016/j.diabres.2008.12.018 [DOI] [PubMed] [Google Scholar] 62.Hearn L, Derry S, Moore RA

Drinking too much caffeine can create a vicious cycle of unrestful sleep, fatigue, and needing more caffeine
