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Following an acute administration of EtOH (5 g/kg, i.p.), KO animals exhibited 30% and 50% less EtOH and AA accumulation in circulation, respectively, suggesting an increased capacity for liver EtOH and AA metabolism in KO mice

Minimizing exposure to toxins and pollutants, such as cigarette smoke and environmental chemicals, can also help maintain optimal glutathione levels by reducing the bodys toxic burden

We conclude that the main function of endogenous GSH is not to limit inflammation but to fine-tune the innate immune response to infection
