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In addition to the whole-body circadian rhythm controlled by the central clock, each organ has its own functional circadian rhythm modulated by a peripheral clock 21,22,23 which is itself regulated by several pathways, including autonomic nerves from the SCN, oscillating/circulating hormones, or indirect behavior regulation such as food intake, movement, and social contact 24,25,26,27,28

doi: 10.1016/j.phrs.2020.104919 145 YanH-fZouTTuoQ-zXuSLiHBelaidiAAet al