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PubMed Research Purposes Only: The information provided in this article is for educational and research purposes only

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Therefore, there is a predominantly Th1 response during the beginning of the follicular phase, the end of the luteal phase, and menstruation, since estrogen and progesterone levels are not elevated [216]

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The disease is caused in most patients by germline inactivating mutations that affect the PRKAR1A gene ( PRKAR1A mutations partly mimic the action of ACTH on adrenal steroidogenic cells

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