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Saxena AR, Frias JP, Brown LS, Gorman DN, Vasas S, Tsamandouras N, et al
Clinical guidelines suggest considering treatment modification if less than 5% weight loss occurs after approximately 12 weeks on a therapeutic dose

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All studies used the same HM, which consisted of a foam core coated in polyurethane material (Technogel, Italia S.R.L., Vicenza, Italy)
