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4 Perspective Ferroptosis is a lipid peroxidation-driven and iron-dependent form of cell death (Chen et al., 2021a)

Blood NADs and Glutathione Metabolites are Perturbed in Various Diseases To explore whether the redox pools were modified by chronic age-related diseases, we examined blood NAD and glutathione metabolites across 11 different diseases, including various cancer types, diabetes (Type II) and neurodegenerative diseases (Parkinsons and Alzheimers)

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In one study, treatment with DMSA after exposure to inorganic mercury caused an elevation of mercury in motor axons, likely due to redistribution of mercury, which was mobilized from nonneural tissues such as the kidneys and liver [86]