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Selhub J, Homocysteine metabolism, Annual Review Nutrition

G.RuffellB

More than 25 million people or nearly 20 percent of Americans aged 40 or over have cataracts in one or both eyes

Although DCA is a relatively weak PDK inhibitor (K i 0.2 mM for PDK2), its effects on aspects of intermediary metabolism are profound and relate directly to the pivotal role the PDC plays in regulating eukaryotic cellular fuel selection and bioenergetics [17, 18]
