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Description
Both types of linkers have been shown to be safe in preclinical and clinical trials
You can see the full numbering of tocopherols in the link below
The underlying pathogenic mechanisms are not fully understood but experimental evidence suggests that osteoblasts (mediators of bone construction) are deficient and their counterparts the osteoclasts have increased survival leading to increased degradation of bony tissue 69
10.1146/annurev.med.51.1.357 [DOI] [PubMed] 4.Green R, Allen LH, Bjrke-Monsen AL et al (2017) Vitamin B12 deficiency
