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The majority of the regulatory control of the GI tract occurs locally and is directed by the brain in the gut, the ENS (46)
The discovery of new lipolytic enzymes and coregulators, the demonstration that lipophagy and lysosomal lipolysis contribute to the degradation of cellular lipid stores and the characterization of numerous factors and signalling pathways that regulate lipid hydrolysis on transcriptional and post-transcriptional levels have revolutionized our understanding of lipolysis
Da Silva C, Wagner C, Bonnardel J, Gorvel JP, Lelouard H
Dosing involves 20-40mcg daily, typically post-workout when muscle tissue is primed for growth
