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examined SLC38A1 expression in 277 AML patients and found that patients with high SLC38A1 expression had a higher risk of adverse karyotypes and a shorter overall survival [30]

RSL3 is an inhibitor of GPx4, and studies have found that the PERK inhibitor GSK414 not only suppresses the expression of the ER stress signaling pathway eIF2/ATF4/CHOP induced by RSL3 but also reduces cellular ferroptosis, improving experimental colitis in mice

Hwang J, Jin J, Jeon S, Moon SH, Park MY, Yum DY
