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It belongs to the gonadotropin family and shares a common subunit with luteinizing hormone (LH), folliclestimulating hormone (FSH), and thyroidstimulating hormone (TSH), but carries a distinct subunit and glycosylation pattern that confer its unique, longacting biological profile

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Physiological activation of brown fat 3-AR through cold stress, (96-98) or direct pharmacological activation (99) rapidly activates non-shivering thermogenesis