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Description
Risk factors for reoperation after lumbar spine surgery in a 10-year Korean National health insurance service health examinee cohort

Additionally, its noted that based on body surface area, the highest tested [subcutaneous] dose (1 mg/kg/day) administered for the longest time (26 weeks) to mice, rats, and monkeys provides safety margins of ~3-fold, 6-fold, and 12-fold to the daily human [subcutaneous] dose of 1.6 mg, respectively. Reproductive and developmental toxicity: SciClone Pharmaceuticals, a biopharmaceutical company, claimed to have successfully completed adequate reproductive toxicology studies on the use of TA-1 in rodents, but the FDA notes that no published nonclinical studies with the data could be identified

Ketone bodies as signaling metabolites

People with certain health conditions, those on higher doses, and those taking it long-term are the risk factors
