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Subcutaneous injections placed too shallow (into the dermis rather than the subcutaneous fat layer) or administered too rapidly produce localized inflammatory responses as the solution disperses unevenly through tissue planes

H., Chen, K

Abstract Valproic acid (VPA) is a broad-spectrum antiepileptic drug and is usually well tolerated, but rare serious complications may occur in some patients receiving VPA chronically, including haemorrhagic pancreatitis, bone marrow suppression, VPA-induced hepatotoxicity (VHT) and VPA-induced hyperammonaemic encephalopathy (VHE)

Neuronal and glial calcium signaling in Alzheimers disease