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The elevated DNA damage and altered DNA methylation are risks for cancer and play essential roles in neurological, and developmental abnormalities and cognitive defects (, , )

Used in the detoxification of harmful elements, cell health and most importantly in skin whitening and skin brightness, glutathione is a naturally occurring antioxidant production in the body

Eligible subjects were then randomly assigned to one of three treatment groups with equal probability: a low-dose GSH group receiving 250 mg GSH per day orally, a high-dose GSH group receiving 1,000 mg GSH per day orally, and a placebo group receiving an inactive substance

However, it should be noted here that only for selenium the median for the IG patients was within the normal range at each time point, whereas median for the CG patients had levels below normal value during most of the postoperative phase (see Fig