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CHEMICAL PEELS Chemical peelings with kojic acid, glycolic acid, and trichloroacetic acid, either alone or in combination, are effective therapy for diffuse melasma and localized hyperpigmentations (lentigo)

However, given the limited efficacy of systemic chemotherapy in ESCC and lack of reliable predictive biomarkers and novel therapeutic targets, there is a pressing need for further exploration

In the absence of MG132, RanBPM overexpression or downregulation elevated or declined p21 protein levels in A549 or H1299 cells, while dysregulation of p21 caused by RanBPM could be blocked by the proteasome inhibitor MG132 (Fig

doi: 10.1111/nure.12080