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10.1074/jbc.M503570200 J

Its consistent use helps fade blemishes, acne scars, and discoloration while improving overall skin texture
CCK is secreted from I-type enteroendocrine cells in the duodenum and small intestine to intestinal lamina propria where it binds to CCK receptors on the vagus nerve terminal, transferring satiety signals to the hypothalamus via the brainstem and pontine parabrachial nucleus [34]

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