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For example, patients who are positive for anti-citrullinated protein antibodies (ACPA) or have elevated C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) often exhibit a more aggressive course of rheumatoid arthritis and may benefit from early, intensive interventions such as TNF inhibitors 67,68,69,70,71,72,73

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Comparatively, curcumin demonstrated similar antioxidant activity to ascorbic acid in the DPPH radical scavenging test