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Wild-type IDH1 overexpression fully rescued the phenotype, demonstrating that the observations are not due to off-target effects (Extended Data Fig

Weve set up a small shelter (cubicle 11 cm) made of aluminum foil covering part of the bacterial lawn with one entrance facing the lawn (Fig

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Nonetheless, the high-fat phenotype can be suppressed by the inactivation of daf-16 , which suggests that the increased fat synthesis is dependent on the inappropriate activation of daf-16 /FoxO