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The study concluded with findings indicating that the vaccine improved survival rates in patients with secondary resistance to immunotherapy compared to chemotherapy, demonstrating better safety outcomes (Besse et al., 2023)

Study selection criteria were defined in terms of population, interventions, comparisons, outcomes and study design (PICOS) to ensure that potentially relevant studies were selected systematically to minimise bias [20, 21]

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Efficacy of dietary lipid control in healing high-fat and high-cholesterol diet-induced fibrotic steatohepatitis in rats
