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Initially, HDACs are generally believed to preferentially target histones, whereas sirtuins exhibit a notable preference for non-histone components in the cytoplasm or within the nucleus, exhibiting complementary functions [51, 52]
Chemical elements play important roles in male reproduction because imbalance of micronutrients or macronutrients may lead to spermatogenesis defects and decreased libido, resulting in male infertility
L-thyroxine requirement rises due to increasing gastric pH, as well as the progressive damage of gastric mucosa [45]
