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We have counted only variants for which the mutation is known and the clinical expression is clearly reported

However, in light of the studies that indicate the increased risk for type 2 diabetes with higher Se intakes, probably the best range of Se in serum/plasma should be around 100110 g/L (57, 234, 235)

However, it is important to understand that animal research does not automatically translate to long-term safety in humans

Although it has not yet reached the clinical application stage, the success of the preliminary experiments demonstrates that this approach holds promise and warrants further exploration and research [18]