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doi: 10.1183/23120541.00180-2023 140 ChangCGuoZHeBYaoW
Common resistance mechanisms include some mutations affecting genetically modified drug targets, membrane permeability, efflux pump systems, and biofilm development (Srisuphanunt et al., 2023)
Celecoxib reverts oxaliplatin-induced neuropathic pain through inhibiting PI3K/Akt2 pathway in the mouse dorsal root ganglion
It impairs keratinocyte proliferation, weakens immune responses, and promotes oxidative damage in the skin
