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This suggests that there might be different lipid metabolic pathways in the two subtypes of HF, and inhibiting myocardial energy deficiency, by restoring ATP-dependent LV relaxation and contraction, might cause beneficial effects in HFpEF [7]

Bordoni L, Sawicka AK, Szarmach A, Winklewski PJ, Olek RA, Gabbianelli R

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It also decreases mitochondrial energy, which slows down motility
