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Nurse practitioner oversight matters here: our NPs are trained to identify contraindications, adjust dosing, and recognize reactions early

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Watch for Signs of Copper Toxicity While GHK-Cu is generally well tolerated, overexposure to copper (especially in individuals with impaired detox pathways) can cause symptoms such as: Nausea or gastrointestinal upset Headaches Mood swings or irritability Metallic taste in the mouth If any of these symptoms occur, discontinue use and contact your healthcare provider

It was also found that ME/CFS patients are unable to dilate their vessels adequately by endothelium-independent vasodilation when given sublingual nitroglycerin to promote relaxation of the vessels