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Description
63 YangW

Structure assignment revealed several key metabolic sites and diverse biotransformation pathways, including ester hydrolysis, aldehyde reduction, aldehyde oxidation, hydroxylation (monohydroxylation and dihydroxylation), glucuronidation, and the cross-combination of these pathways

Soria, A

In two studies in rats, no teratology was observed when 512 mg/kg of sulfamethoxazole was used in combination with 128 mg/kg of trimethoprim