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[39] [40] RSSR' + 2 GSH RSH + R'SH + GSSG where R and R' are parts of the micro-nanogel structure, and GSSG is oxidized glutathione (glutathione disulfide)

For example, administration of the cysteine-donor N-acetyl cysteine (NAC) in humans significantly increases blood [6264] and muscle [65, 66] GSH levels, and in vitro studies show methionine supplementation to have beneficial effects on GSH hepatocyte concentrations [67]