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Although it seems to be a perfect model for PD studies, there are criticisms that the rotenone-induced PD model is difficult to reproduce and likely to cause mortality (Hglinger et al., 2003

This gene codes for the MTHFR enzyme, a key enzyme in the methylation cycle
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Excesses of certain nutrients (like fat-soluble vitamins) can cause toxicity because your cats body has a limited ability to eliminate what it doesnt need
