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Funding CWI is supported by the Interdisciplinary Center for Clinical Research (IZKF) at the University of Wrzburg (A-303 to CWI, A-421 to CWI and JWi, N-362 to CWI), by the Deutsche Stiftung Neurologie and the ParkinsonFonds Germany and by the University Research Funds of the State of Bavaria

In this cross-sectional study, 512 consecutive participants were included

Therefore, a decrease in intestinal dopamine levels is closely related to the development of IBD

We further demonstrate that a senolytic FOXO4-D-retro-inverso-isoform peptide (FOXO4-DRI) promotes apoptosis and decreases G0/G1 phase cells in pro-senescence models of keloid organ cultures and fibroblasts, accompanied with p53-pS15 nuclear exclusion